Rate limiting step of TCA :
High-Yield Explanation
3 enzymes which are rate limiting in TCA cycle Irreversible steps of TCA 1. Citrate Synthase 1. Citrate Synthase (preferred) 2. Isocitrate Dehydrogenase 2. Alpha-Ketoglutarate Dehydrogenase. 3. Alpha-Ketoglutarate Dehydrogenase