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Physiology Endocrinology and Reproduction d763e59c

Insulin acts through which channel/transporter-

A
GLUT-1
B
GLUT-4
C
SGLT-1
D
SGLT-2
High-Yield Explanation
Ans. is 'b' i.e., GLUT-4 * Glucose is transported into the cells by two mechanismsi) Facilitated diffusion By glucose transporters (GLUT)ii) Secondary active transportBy sodium dependent glucose transporter (SGLT)* Insulin increases glucose uptake by increasing the GLUT4 on the cell membrane. Thus, insulin promotes facilitated diffusion i.e. diffusion along concentration gradient (not against concentration gradient). So, option b is incorrect.

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