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Pathology Endocrinology d7284631

The feature that differentiate a follicular carcinoma from a follicular adenoma of thyroid is

A
Nuclear pleomorphism
B
Huhle cell change
C
Capsular invasion
D
Absence of colloid
High-Yield Explanation
Follicular adenomas and carcinomas both are composed of well - differentiated follicular epithelial cells;the latter are distinguished by evidence of capsular and/or vascular invasion. They both have fairly uniform cells forming small follicles containing colloid. So there is no reliable cytological difference between them. (ref:ROBBINS Text book of pathology) REf img :

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