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Pharmacology Endocrinology d708cba3

Which of the following is/ are side effect/s of growth hormone administration?

A
Pain at injection site
B
Glucose intolerance
C
Hypothyroidism
D
All the above
High-Yield Explanation
Ans. is 'd' i.e., All the above Adverse effects of growth hormone* Somatropin and somatrem are recombinant GH analogues.* Somatrem has an additional methionine residue and is more immunogenic than somatropin, but allergic reactions or resistance to treatment are not a problem.* Pain at injection site and lipodystrophy can occur.* Glucose intolerance, hypothyroidism (due to unmasking of TSH deficiencv), salt and water retention, hand stiffiress, myalgias, headache are the possible adverse effects* Rise in intracranial tension occurs in few cases.

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