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Biochemistry miscellaneous d6b8a29d

Mucopolysaccharidoses are caused by

A
An increased rate of synthesis of proteoglycans
B
Defects in the degradation of proteoglycans
C
The synthesis of polysaccharides with an altered structure
D
An insufficient amount of proteolytic enzymes
High-Yield Explanation
Mucopolysaccharides are excreted in urine in abnormal amounts in the group of lysosomal storage disorders known as mucopolysaccharidoses. They can be detected by 2D gel electrophoresis techniques; some mucopolysaccharides can also be detected by simple urine screening tests like CPC test, Cetavlon test and Alcian blue staining.Ref: D M Vasudevan 7th edition Page no: 80

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