In a case of ectopic pregnancy, medical treatment is contraindicated if:

Criteria for medical treatment 1) Ectopic mass <3.5cm – the presence of fetal cardiac activity is a contra-indication to medical treatment 2) No fetal cardiac activity 3) Initial hCG <3000iu/l 4) The patient must be hemodynamically stable, with no signs or symptoms of active bleeding or hemoperitoneum. 5) She should not have any contraindications to the use of methotrexate.