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Pharmacology Autonomic nervous system d6ad8a8e

A patient present to emergency with pinpoint Pupil,salivation, lacrimation, tremors and red tears. Plasma chlolinesterase level was 30% of normal. Most probable diagnosis is

A
Organophosphate poisoning
B
Datura poisoning
C
Opioid poisoning
D
Pontine hemorrhage
High-Yield Explanation
These are characteristic features of anti-cholinestearse(organophosphate and carbamate) poisoning. Features of Organophosphate poisoning: Muscarinic symptoms: Pin point pupil, salivation,lacrimation, urination, defecation, gastrointestinal distress, vomiting, bronchospasm, bradycardia Nicotinic symptoms: Fasciculations and fibrillations of muscle, tachycardia, tachypnea CNS symptoms: Temors, giddiness, ataxia, coma Red tears: Due to accumulation of porphyrin in the lacrimal glands Ref-Katzung 12/e p110

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