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Anaesthesia Muscle Relaxant d6777952

A 62-year-old female was scheduled for mechanical ventilation for respiratory failure. She was administered pancuronium as a muscle relaxant before intubation. Which of the following statement is accurate regarding pancuronium?

A
Tetanic tension is poor
B
Muscle fasciculations are observed at the onset
C
Autonomic ganglia are stimulated
D
Predominantly histamine release
High-Yield Explanation
Answer: a) Tetanic tension is poorNon-depolarizing muscle relaxants act as pharmacological antagonists at the skeletal muscle end-plate.It acts by competitive antagonism.These agents show post-tetanic potentiation, while the tetanic tension declines rapidly.Response to the tetanic stimulus is unsustained with non-depolarizing muscle relaxants, whereas it is sustained during phase I block with depolarizing muscle relaxants.

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