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Ophthalmology General d564b0cd

A 30 year old female found to have 'angioid streaks' on retina during ocular examination. Which of the following systemic illness is associated with this clinical presentation?

A
Tay Sach's disease
B
Vogt Koyanagi syndrome
C
Wilson's disease
D
Pseudoxanthoma elasticum
High-Yield Explanation
Angioid streaks appear as irregular, jagged tapering lines that radiate from the peripapillary retina into the macula and peripheral fundus. The streaks represent linear, crack-like dehiscence in Bruch's membrane. Systemic diseases associated with angioid streaks: Pseudoxanthoma elasticum Paget disease of bone Ehlers-Danlos syndrome Hemoglobinopathy Hemolytic disorders Ref: Fletcher E.C., Chong N., Augsburger J.J., Correa Z.M. (2011). Chapter 10. Retina. In P. Riordan-Eva, E.T. Cunningham, Jr. (Eds), Vaughan & Asbury's General Ophthalmology, 18e.

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