The lesion shown below is caused by

Human papillomavirus (HPV) which is the most common sexually transmitted infection, is a cause of anal dysplasia and cancer.The approximately 40 HPV subtypes that can cause anogenital infections are divided into:1. Low-risk types (e.g. types 6 and 11) that cause anal warts (condyloma acuminata)2. High-risk types (e.g. types 16, 18 and 33) that can cause anal dysplasia and cancer.HPV infection is associated with cervical, vulvar, vaginal, and penile cancers, and some patients have HPV-related dysplasia or cancer in multiple sites. Approximately 90% of anal cancers are attributable to HPV infection.