True statement regarding carbonic anhydrase inhibitors are all except

Carbonic anhydrase inhibitors exhibit no competition as they are not structural analogs and they bind weakly-reversible.They are called self limiting diuretics include acetazolamide and brinzolamide ,dorzolamide used in catamenial epilepsy,mountain sickness,glaucoma anle closure. Ref: KD T 7th ed pg 586