Full 2L QBank
Microbiology Immunology d4aca0fc

Relative to the primary immunological response, secondary and later booster responses to a given hapten-protein complex can be associated with which one of the following?

A
Lower titers of antibody
B
Increased antibody affinity for the hapten
C
Decreased antibody avidity for the original hapten-protein complex
D
Maintenance of the same subclass, or idiotype, of antibody produced
High-Yield Explanation
With repeated immunization, higher titers of all antibodies are observed, and, as priming is repeated, the immune response recruits B cells of progressively greater affinity. The affinity of antibody for a hapten-protein complex rises, cross-reactivity also rises, and the response becomes wider in specificity. As the number of antigenic sites detected per reacting particle increases, the avidity increases. In addition to shifts in the class of immunoglobulin synthesized in response to an antigen (IgM to IgG), shifts also may occur in the idiotype of antibody.

Related Microbiology MCQs

Practice 2,00,000+ NEET PG Questions Free

Timed mock tests, mistake queue analytics, audio lectures & zero attempt limits on i❤️Exams.

Start Free Mock Test Now