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Pharmacology Hypeension, Arrhythmias, Dyslipidemia d47f30f2

All of the following antihypeensive drugs increase plasma renin activity except:

A
Clonidine
B
Hydralazine
C
Nifedipine
D
Captopril
High-Yield Explanation
Plasma renin activity is increased by reflex increase in sympathetic discharge. Clonidine decreases central sympathetic outflow and thus will decrease the plasma renin activity. Vasodilators and ACE inhibitors result in reflex increase in plasma renin activity.

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