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Pharmacology Chemotherapy: General Principles d46a4216

A patient has hepatic encephalopathy. The drug of choice for gut sterilization in this patient is:

A
Neomycin
B
Netilmicin
C
Bleomycin
D
None of the above
High-Yield Explanation
Ans. (A) Neomycin(Ref: KDT 8/e p799)When administered by oral route, neomycin is not absorbed and kills intestinal bacteria. These bacteria are responsible for the generation of NH3 Excessive ammonia can result in hepatic encephalopathy. Neomycin decreases NH3 by killing intestinal bacteria.

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