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Pathology General pathology d43669d3

Cells are most radio-resistant in

A
S phase
B
M phase
C
G1 phase
D
G2 phase
High-Yield Explanation
Cell cycle Correct sequence: G0-G1-S-G2-M Most impoant checkpoint: G1-S Cellular content doubled in: S phase Cyclins D,E,A,B appears sequentially Cyclin D - first to increase in cell cycle Cyclin D - controls G1-S transition P16 (CDKN2A), P53& RB - Induce cell cycle arrest at G1-S Cyclin B - controls G2-M transition Fixed time is required for: S & M phase Most radio-resistant phase: S Most radio-sensitive phase: M

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