Glomerular filtration rate stas declining at what age?
High-Yield Explanation
Glomerular filtration rate (GFR) is the volume of fluid filtered from the renal (kidney) glomerular capillaries into the Bowman&;s capsule per unit time.The normal range of GFR, adjusted for body surface area, is 100-130 ml/min/1.73m2 in men and women. In children, GFRmeasured by inulin clearance is 110 ml/min/1.73m2 until 2 years of age in both sexes, and then it progressively decreases. After age 40, GFR decreases progressively with age, by about 0.4 - 1.2 mL/min per yearRef: Ganong&;s review of medical physiology; 24th edition; page no; 679