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Medicine Disorder of Metabolism & Connective Tissue d394f2eb

Which of the following is true about findings of Polyarteritis nodosa?

A
There is tear in the lamina Dura
B
Micro Aneurysm formation in the large blood vessel
C
Nodules are formed in skin which are clinically palpable
D
Chain of beads appearance
High-Yield Explanation
Ans. is 'c' i.e., Nodules are formed in skin which are clinically palpable Skin manifestation of PANo Tender erythematous noduleso Palpable purpurao Livedo reticularso Ulcerso Bullowor vesicular eruptionso The palpable purpuris lesion seen in PAN are identical to those seen in other forms of vasculitis usually associated with small vessel disease (e.g. H.S. purpura ANCA associated vasculitis and mixed cryoglobulinemia),o Biopsy reveals leucocytoclastic vasculitis most prominent in post capillary venules.

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