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Pharmacology General d34a058c

Which of the following statements is NOT TRUE about NSAIDs ?

A
Acetyl salicylic acid is an irreversible inhibitor of COX enzyme.
B
Acetylsalicylic acid reduces in vivo synthesis of prostaglandins.
C
Its clearance is independent of plasma concentration
D
Antiplatelet effect of low dose aspirin is related to pre-systemic COX inhibition
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