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Pediatrics Nephropathy d3198f84

A 9- years old child has steroid dependant nephrotic syndrome for the last 5 years. He has received corticosteroids almost continuously during this period and has Cushingoid features. The blood pressure is 120/86 mmHg and there are bilateral subcapsular cataracts. The treatment of choice is:

A
Levamisole.
B
Cyclophosphamide.
C
Cyclosporin A.
D
Intravenous pulse corticosteroids.
High-Yield Explanation
Ans. is 'b' i.e. cyclophosphamide If a child with nephrotic syndrome on steroid develops features of corticosteroid toxicity (cushingoid features, hypertension, cataract and growth failure) then cyclophosphamide should be used.

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