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A 47 year old man presents to the emergency room with sudden onset of severe upper abdominal pain with vomiting. The pain is focused in the epigastrium with radiation to the back. Serum amylase levels are 2000 U/L. Which of the following are the most commonly encountered predisposing factors for this patient's condition?

A
Alcohol use and gallstones
B
Helicobacter pylori infection and excess gastric acid secretion
C
Hepatitis B infection and iron overload
D
Obesity and high serum cholesterol
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