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Medicine All India exam d22d3b0d

gordons syndrome is charecterized by by al except ?

A
hyperkalemia
B
metabolic acidosis
C
low rennin and low aldosterone
D
hypotension
High-Yield Explanation
* Type II pseudohypoaldosteronism in adults with HT( Gordon&;s syndrome ) .primary defect may be related to "enhanced Cl reabsorption in early distal tubule".../imit Na delivery to more distal tubule, decreased lumen negativity, impaired K secretion due to voltage-shunt effect -- Increased NaC1 reabsorption expand ECF volume...HT and suppress RAAS -- Hyper K contributes to inhibition of renin secretion -- PA..normal or suppressed depending upon balance between inhibitory effect of volume expansion and stimulatory effect of hyperkalemia harrisons 21st ed

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