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General Medicine General d207ad9e

A patient presents to a physician because of a markedly inflamed and painful great toe. Physical examination additionally demonstrates small nodules on the patient's external ear. Aspiration of the metatarsal-phalangeal joint of the affected toe demonstrates needle-shaped, negatively birefringent crystals. Of which of the following are the crystals most likely composed?

A
Bile pigments
B
Calcium pyrophosphate
C
Cystine
D
Monosodium urate

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