True about Rheumatic hea disease and Rheumatic fever is/are -

Ref: R Alagappan - Manual of Practical Medicine 4th Edition.pg no: 146 Rheumatic Fever Acute, recurrent, inflammatory disease, mainly of children (aged 5-15 years), typically occurring 1-5 weeks after group A streptococcal infection. Pathophysiology 1. Cross reactivity of host antistreptococcal antibodies to cardiac antigens 2. Microbe initiated autoimmune reactivity.