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Pathology General d1edf376

A diabetic patient is undergoing dialysis. Aspiration done around the knee joint would show which of the following?

A
A- b2 microglobulin
B
AA
C
AL
D
Lactoferrin
High-Yield Explanation
Chronic renal failure patients undergoing long term hemodialysis develop amyloidosis. Amyloidosis in such cases is associated with the deposition of a protein called A- b2 microglobulin. Such amyloid deposits are common in synovium, joints and tendon sheaths. So an aspirate obtained from knee joint would likely reveal A- b2 microglobulin.Ref: Pathologic Basis Of Disease, Robbins, 6th Edition, Page 253; 7th Edition, Page 260, 261.

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