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Biochemistry General d1b93363

The term modified base refers to

A
Purine or pyrimidine attached to deoxyribose
B
A purine or pyrimidine that has been altered
C
A nitrogen containing ring other than a purine or pyrimidine that is part of a nucleotide
D
A purine or pyrimidine attached to a sugar by O-glycoside linkage
High-Yield Explanation
A modified base is one that has been modified after nucleic acid chain has been formed. These bases are modified by methylation, reduction, acetylation or glycosylation. In t-RNA there are many modified bases, e.g. dihydrouridine, ribothymidine, pseudouridine, and 7-methylguanosine. In DNA, the most common modified base is 5-methylcytosine. Other important modified bases are acetylcytosine and dimethyladenine.

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