A five year old boy presents with precocious pubey and a blood pressure of 130/80 mmHg. Estimation of which of the following will help in diagnosis ?

Ans. is `d' i.e. | 11 deoxycoisol o At the age of 5-6 years, BP in excess of 115/75 mm Hg is considered as hypeesion (This boy has BP 130/80). o So, the boy in this question has : ? i) Precocious pubey ii) Hypeension o Precocious pubey in male, with salt retention and hypeension, occurs due to deficiency of 11-13 Hydroxylase which catalyzes the conversion of 11 deoxycoisol to coisol.