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Biochemistry Enzymology d13e9991

Which of the following is a lyase

A
Aldolase
B
Fumarase
C
Decarboxylase
D
All of the above
High-Yield Explanation
All of the above i.e. Fumarase, Aldolase, Decarboxylase are Lyases. Lyases are enzymes which can either break a bond or make a bond but they do not require water or ATP. The EC No. is 4. Fumarase is a Lyase (also known as Hydratase enzyme which can add or remove water but bond is not broken). Aldolase A & B both are Lyases. Simple Decarboxylases are Lyases. EXTRA EDGE: The other examples of Lyases are: Synthase - Link two molecules without involvement of ATP. Desulfhydrase - Remove H2S from substrate. Enzyme of Oxidative decarboxylation is a Dehydrogenase, so belongs to EC No.= 1 as compared to simple decarboxylases which are Lyases.

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