Which of the following is NOT associated with Crohn's disease:

Ans. (c) Toxic megacolonRef. Harrison's 17th ed. Ch. 289* Crohn's disease is a chronic, recurrent disease characterized by patchy transmural inflammation involving any segment of the gastrointestinal tract from the mouth to the anus but most common site is Ileum.* Crohn's disease is one of the two main forms of Inflammatory bowel disease and is also known as Granulomatous colitis.* Earliest manifestation is Apthous ulcers.* Skip lesions, stricture formation, string sign of kantor is also seen.* Hallmark feature of crohn's is fistula formation.* Cobble stone appearance is seen on X-Ray.* NOTE: Toxic mega colon is seen in Crohns disease but most commonly toxic megacolon is seen in Ulcerative colitis.