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Pharmacology Chemotherapy: General Principles d0cb6783

Which of the following statements is not true about rifabutin as compared to rifampicin?

A
It has longer half-life than rifampicin
B
It is more effective for newly diagnosed TB as compared to rifampicin
C
It has lesser incidence of drug interactions as compared to rifampicin
D
It is more effective against MAC as compared to rifampicin
High-Yield Explanation
Ans. (B) It is more effective for newly diagnosed TB as compared to rifampicin(Katzung 13th/817,820) RifampicinRifabutinHalf lifeShorterLongerCYP inhibition (drug interactions)MarkedWeakEfficacy against Mycobacterium tuberculosisMoreLessEfficacy against MACLessMoreHepatotoxic potentialPresentAbsent
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