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Pathology Hemolytic anemia d0a9e9da

All cause Reticulocytosis EXCEPT:

A
Aplastic anemia
B
Thalassemia
C
Sickle cell anemia
D
Chronic blood loss
High-Yield Explanation
Ans. (a) Aplastic anemiaRef: Robbiris pathology 9th ed. /631* Aplastic anemia is characterized by destruction of bone marrow and thereby reduction in pluri-potent stem cells and their progeny.Henceforth the production of reticulocytes is less.* Thalassemia and sickle cells are hemolytic anemias having extra-vascular hemolysis and thereby reticulocytosis.* In chronic blood loss the loss of RBC provoke the bone marrow to be more aggressive and release reticulocytes in circulation.* REMEMBER: Reticulocytopenia may be a result of viral Parvovirus B19 infection, which invades and destroys red blood cell precursors and halts the red cell production.

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