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General Medicine General d07e44ee

A scientist has developed an adipocyte cell line that, at 42degC, cannot degrade triglycerides to glycerol and free fatty acids. At 25degC, the triglyceride degradation is normal. Which one of the following best reflects enzymes in which a temperature-sensitive mutation may lead to this phenotype?

A
Protein Kinase A - yes; Adenylate Kinase - no; Insulin Receptor - no; Glucagon Receptor - yes; Glycerol Kinase - yes
B
Protein Kinase A - no; Adenylate Kinase - no; Insulin Receptor - yes; Glucagon Receptor - no; Glycerol Kinase - yes
C
Protein Kinase A - yes; Adenylate Kinase - no; Insulin Receptor - no; Glucagon Receptor - yes; Glycerol Kinase - no
D
Protein Kinase A - no; Adenylate Kinase - yes; Insulin Receptor - yes; Glucagon Receptor - no; Glycerol Kinase - no

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