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Biochemistry General d06a447d

The secondary structure of prion paicles is:

A
Alfa helix
B
Beta bends
C
Beta sheets
D
Beta turns
High-Yield Explanation
C i.e. Betasheets There is no difference in amino acid & gene sequence, primary structure & post translational modifications between normal cellular isoform of non infectious (host) prion protein (PrPC) and infectious (pathological) prion proteins (PrPsc). The key to becoming infectious lies in 3 dimensional conformation i.e. a number of a -helices present in non infectious PrPC are replaced by /3 sheets in infectious (PrPse) formQ.

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