Which of the following is not true about xenon anesthesia
High-Yield Explanation
Xe has a very low blood-gas solubility coefficient (0.115) and produces rapid induction of and emergence from anesthesia. Xe is not teratogenic, does not undergo biotransformation, and exes anesthetic and analgesic effects under normal atmospheric pressure conditions (1.0 MAC = 71%). Xe is derived from a paicle decay of radioactive heavy metals such as uranium and thorium. Xe naturally occurs in the atmosphere in trace amounts (1:11.5 million ) and is extracted from liquefied air by sequential cryogenic fractional distillation. Unlike volatile anesthetics and N2O, which produce diverse hemodynamic actions in the absence or presence of hea disease, Xe is essentially devoid of major cardiovascular effects. Xe did not affect voltage-gated Ca2+ currents and caused minimal inhibition of transient outward K+ currents in human atrial myocytes in vitro. Ref: Miller's anesthesia 8th edition Ref: Morgan & Mikhail's clinical anesthesiology 6e