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Most impoant investigation for diagnosis of Zollinger Ellison syndrome is: March 2013

A
Ca2+ infusion test
B
Secretin injection test
C
ACTH stimulation test
D
Steroid assay
High-Yield Explanation
Ans. B i.e. Secretin injection test Gastrinoma/ ZES MC site: Duodenum Non beta cell tumour, Neuro-endocrine tumour/ NET secreting: Gastrin Most impoant investigation: Secretin injection test DOC for ZES: Proton pump inhibitors Hepatic metastasis occurs (33%)

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