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General Medicine General cf1ab0f0

A 41-year-old woman has had diminished hearing for the past 4 months. On physical examination, she has decreased hearing on the left. Sound lateralizes to the right ear on the Weber tuning fork test. A head MRI shows a sharply circumscribed, 4-cm mass adjacent to the left pons that extends toward the left inferior cerebellar hemisphere. A smaller 1-cm lesion is in a similar location on the right. Family screening reveals a similarly affected 38-year-old sibling. An inherited mutation involving which of the following genes is most likely to be present in this patient?

A
NF2
B
TP53
C
PTCH
D
TSC1

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