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Pediatrics General cf0999e9

Injection of Glucagon is effective for management of persistent hypoglycemia in all EXCEPT –

A
Large for date baby
B
Galactosemia
C
Infant of diabetic mother
D
Nesidioblastosis
High-Yield Explanation
Hypoglycemia in hyperinsulinmic state require IM glucagon as treatment. Glucagon increases glucose level in blood by Glycogenolysis and Gluconeogenesis. But in galactosemia - Liver is the first organ to be affected, so glucagon will unable to increase glucose as glycogenolysis and gluconeogensis can not occur ion already damaged liver. Nesidioblastosis : It is persistent hyperinsulinemic hypoglycemia occurs due to 0 - cell hypertrophy in infant of diabetic mother due to continuous maternal hyperglycemia. Glucagon is effective in controlling such a hypoglycemic condition.

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