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Pharmacology General cf08dc5f

Dose of drug require no or minor adjustment in renal failure, except -

A
Doxycycline
B
Vancomycin
C
Chloramphenicol
D
Clindamycin
High-Yield Explanation
Ans. is 'b' i.e., Vancomycin o Vancomycin causes renal toxicity which is dose related therefore significant dose reduction is needed in renal failure. o Rest of the drugs asked in the question are metabolised mainly in liver therefore no adjustment needed in renal failure.

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