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General Medicine General cee9783c

A male presenting with respiratory distress is put on a ventilator. Tracheal culture was obtained and sent for diagnosis. In the meanwhile, he was empirically staed on amikacin and ceftriaxone. Culture repo after 48 hrs shows growth of Klebsiella pneumoniae which is ESBL +ve on antimicrobial susceptibility testing. The modification needed in his antibiotic treatment is:

A
Replace ceftriaxone with ceftazidime
B
Omit amikacin and add a quinolone
C
Replace ceftriaxone with imipenem
D
Continue the same antibiotics at higher doses

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