Growth stimulators & inhibitors are produced by:

(A) Eosinophil # Eosinophil granulocyte: Eosinophil granulocytes, usually called eosinophils (or, less commonly, acidophils), are white blood cells that are one of the immune system components responsible for combating infection and parasites in vertebrates.> Along with mast cells, they also control mechanisms associated with allergy and asthma.> They are granulocytes that develop during Haematopoiesis in the bone marrow before migrating into blood.> Functions of eosinophils: Following activation, eosinophils effector functions include production of:- Cationic granule proteins and their release by degranulation.- Reactive oxygen species such as superoxide.lipid mediators like eicosanoids from the leukotriene (e.g., LTC4, LTD4, LTE4) & prostaglandin (e.g., PGE2) families.- Enzymes, such as elastase. Growth factors such as TGF beta, VEGF, and PDGF. Cytokines such as IL-1, IL-2, IL-4, IL-5, IL-6, IL-8, IL-13, and TNF alpha.