Pharmacology Other topics and Adverse effects ce659969

All of following statements about are true about 6-mercaptopurine EXCEPT:

It is metabolized by xanthine osidase

It does not cause hyperuricemia

Its dose should be reduced when allopurinol is given concurrently

It is an active metabolite of azathioprine

High-Yield Explanation

(Ref: KDT 6/e p823, 824) All anticancer drugs can result in hyperuricemia by causing the destruction of excess cells. Azathioprine is an immunosuppressant drug that acts by generating 6-MP

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All of following statements about are true about 6-mercaptopurine EXCEPT:

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