A patient has undergone a renal transplantation 2 months back and now presented with difficulty in breathing. X-ray showed bilateral diffuse interstitial pneumonia. The probable etiologic agent would be :
High-Yield Explanation
Cytomegalovirus (CMV) is the largest virus in the herpes family.
It is transmitted transplacentally from a latent mother to foetus.
Postnatal infections are usually acquired by means of sexual intercourse, blood transmission and organ transplantation , clinical disease resembles infectious mononucleosis .
It may cause hepatitis and pneumonitis.
For treatment Ganciclovir is the drug of choice.
Ref : textbook of microbiology, C P Baveja, 5th edition , Pg no:446