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Medicine Miscellaneous (Endocrinology) ce2672dc

Best test for diagnosis of Carcinoid tumor:

A
24 hour urinary 5H.I.A.A
B
24 hour catecholamines
C
24 hour vaniylmandelic acid levels
D
24 hour metanephrine levels
High-Yield Explanation
Ans. (a) 24 hour urinary 5H.I.A.ARef: Harrison 19th ed. 1564-65* 5-HLAA is the major urinary metabolite of serotonin, a ubiquitous bioactive amine. Serotonin, and consequently 5-HLAA, are produced in excess by most carcinoid tumors, especially those producing the carcinoid syndrome of flushing, hepatomegaly, diarrhea, bronchospasm, and heart disease.

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