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Microbiology Immunology ce234c1c

Innate immunity is stimulated by which part of bacteria?

A
Carbohydrate sequence in cell wall
B
Flagella
C
Bacterial cell membrane
D
Nucleus
High-Yield Explanation
ANSWER: (A) Carbohydrate sequence in cell wallREF: Ganong's physiology 23rd edition page 69, htty://www. ncbi.nlm.nih.gov/pubmed/11581570Innate immunity does not have the specificity of adaptive immunity, but is capable of distinguishing self from nonselfBacterial lipopolysaccharides (LPS) are the major outer surface membrane components present in almost all Gram-negative bacteria and act as extremely strong stimulators of innate or natural immunity in diverse eukaryotic species ranging from insects to humans.LPS consist of a poly- or oligosaccharide region that is anchored in the outer bacterial membrane by a specific carbohydrate lipid moiety termed lipid A. The lipid A component is the primary immunostimulatory centre of LPS.

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