Which of the following hormones stimulates gluconeogenesis?

Ans. B. Glucagona. The balance and integration of the metabolism of fats and carbohydrates are mediated by the hormones insulin, glucagon, epinephrine, and norepinephrine.b. All of these hormones exercise acute effects upon metabolism. Glucagon stimulates gluconeogenesis and blocks glycolysis.c. When blood sugar levels get low, the a cells of the pancreas release glucagon. The main targets of glucagon are the liver and adipose tissue.d. In the liver, glucagon stimulates the cyclic AMP-mediated cascade that causes phosphorylation of phosphorylase and glycogen synthesis.e. This effectively turns off glycogen synthase and turns on glycogen phosphorylase, thereby causing a breakdown of glycogen and a production of glucose in liver, which ultimately raises blood glucose levels.f. Insulin and glucagon are two antagonistic hormones that maintain the balance of sugar and fatty acids in blood. Insulin is produced by the cells of the pancreas and its release is stimulated by high levels of glucose in the blood. It has a number of effects, but its major effect is to allow the entry of glucose into cells.g. Insulin also allows the dephosphorylation of key regulatory enzymes. The consequence of these actions is to allow glycogen synthesis and storage in both muscle and liver, suppression of gluconeogenesis, acceleration of glycolysis, promotion of the synthesis of fatty acids, and promotion of the uptake and synthesis of amino acids into protein.h. All in all, insulin acts to promote anabolism.