Reverse transcriptase inhibitors are given for:

Ans. (a) HIVKDT 6th ed. 770* ss viral RNAReverse Transcriptase-----------------ds viral DNA.* Reverse transcriptase inhibitors are drugs that are active against HIV, which is a retrovirus.2 class of reverse transcriptase inhibitorsNeucleoside Reverse Transcriptase Inhibitors (NRTI)Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTI)* ZIDOVUDINE* STAVUDINE* DIDANOSINE* LAMIVUDINE* ABACAVIR* ZALCITABINE* EFAVIRENZ* NEVIRAPINE* DELAVIRDINE Rememberd as "END"Also Know * ZIDOVUDINE# Most commonly used NRTI in the treatment of HIV# Used as prophylaxis in needle stick injury and to decrease vertical transmission from HIV mother to fetus.# Side effect: bone marrow suppression.* Drug of choice for decreasing vertical transmission from HIV mother to fetus: NEVIRAPINE* Safest NRTI: LAMIVUDINE* All NRTIs casues acute pancreatitis and peripheral neuropathy.# Maximum risk of acute pancreatitis with: DIDANOSINE# Maximum risk of peripheral neuropathy with: STAVUDINE