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Microbiology Systemic Bacteriology (Haemophilus, Yersinia, Spirochaetes, Ricketssia, Chlamydia, Mycoplasma and Miscellaneous Bacteria) cd6c7100

Mechanism of action of cholera toxin is through:

A
Gangliosides
B
Adenyl cyclase
C
Gangliosides + adenyl cyclase
D
Exotoxin
High-Yield Explanation
Cholera enterotoxin Light toxin: binds with ganglioside in epithelial cell membrane Heavy toxin: activates adenyl cyclase in epithelial cell wall which increase cAMP, leading to outpouring of isotonic fluid in lumen of intestine

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