A 1–year–old child presented with a swelling in the left flank with episodes of flushing, diarrhea, sweating and bone pain. The diagnosis is –

Clinical manifestations of neuroblastoma Because neuroblastoma arises from neural crest derivatives of sympathetic nervous system, it produces catecholamines. So, it may cause clinical feature due to : --> 1. Primary tumor          2. Metastais          3. Catecholamine secretion