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Pharmacology General cd394cfd

A patient complains of muscle weakness. It was reversed on administration of neostigmine,because ?

A
It blocks action of acetylcholine
B
It interferes with the action of amine oxidase
C
It interferes with the action of carbonic anhydrase
D
It interferes with the action of acetylcholine esterase
High-Yield Explanation
Ans. is 'd' i.e., It interferes with the action of acetyl cholinesterase o Neostigmine acts by inhibiting the enzyme acetylcholinesterase. This enzyme is involved in degradation of ACh, consequently neostigmine increases the synaptic level of ACh. Muscle weakness can be improved by stimulation of NM receptor at muscle end plate due to increased ACh.

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