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Pharmacology Epilepsy cd348146

A patient on phenytoin therapy develops depression, for which he was prescribed tricyclic anti-depressants. He now complains of lassitude and his Hb reading is 8 gm/dl, the next step in the management of this patient is:

A
Chest X ray
B
MCV should be estimated
C
GGT should be estimated
D
None of the above
High-Yield Explanation
Ans. (B) MCV should be estimated(Ref: KD T 8/e p441)Phenytoin can induce folate deficient megaloblastic anemia that can be diagnozed by measuring MCV.

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