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Microbiology Bacteriology ccf5808d

Which of the following statements about Corynebacterium diphtheria is false

A
Toxin production is mediated by native chromosome
B
Organism may be identified by tests for toxigenicity
C
Toxin acts by inhibiting protein synthesis
D
Toxin may affect the hea and nerves
High-Yield Explanation
The toxigenicity of diphtheria bacillus depends on the intercellular presence of corynephage (tox+), which acts as the genetic determinant controlling toxin production. The toxin produced by all the strains of the diphtheria bacilli is qualitatively similar. The standard strain almost universally used for toxin production is the Park-Williams 8 strain. The toxin acts by inhibiting protein synthesis. It has a special affinity for ceain tissues such as myocardium, adrenals and nerve endings. Reference: Textbook of Microbiology; Anathanarayan and panicker's; 10th edition; Page no: 240

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